瑞士，星期五, 2020年2月28日 10:35PM 欧洲中部时间
Demiurge致力于利用AI为2019新型冠状病毒（COVID-19）筛选新型候选治疗药物。基于Demiurge开发的精确广谱病毒学模型，我们对已发表的COVID-19研究和临床数据进行了深入分析。
开发针对危重症患者的有效治疗方案至关重要，因为与SARS-CoV和MERS-CoV相比，COVID-19的危重症患者死亡率更高。
同样重要的是，针对危重症患者的有效治疗方案最好是基于价格低廉、供给广泛的成熟药物，使抗疫能力不同的国家都可以迅速有效地降低COVID-19危重症患者的死亡率。
我们特此正式宣布发现以下旨在降低COVID-19危重症患者死亡率的高效安全的新型候选治疗方案：
在慢性病领域，药物专利的排他性和药物销售的独家性有效激励医药企业完成漫长而昂贵的新药开发，最终普惠大众。但是在流行病领域，时间是最为稀缺的要素。公众对治疗药物需求的紧迫性和药企对治疗药物供给的独家性通常在时间上是难以兼顾的。然而我们相信，在对抗流行病对生命的威胁时，深耕于医药事业的企业和个人都会将公众福祉放在首位。争分夺秒，阻击病毒。
因此，面对COVID-19, Demiurge决定第一时间向公众公布我们上述的进一步发现，放弃平常时期申请专利保护、独家权益合作等环节。以期能尽吾之所长，协同业界上下游，开展伊立替康和依托泊苷的联合疗法的超说明书用药。
关于Demiurge Technologies AG
Demiurge Technologies是一家以研究为基础的AI技术与生物医药公司，致力于将公开的海量生命科学数据转换为精确疾病模型。Demiurge创新地建立了利用全球医药三期临床试验结果预测的准确性来验证并改良精准疾病模型的科学进化闭环。同时Demiurge 致力于将精准疾病模型发现的创新药物进行商业化开发。 Demiurge于2016年开始运营，总部位于瑞士。
AI已成为一种新型强大的技术方法，它可以帮助人类更深入地了解疾病和更快地发现药物。但AI必须经过严格的测试，在公众的监督下证明其价值。Demiurge已经完成了90多个三期临床试验结果的预测，实现了大于80%的准确率。同时，我们在推特（Twitter）上邀请公众参与见证我们对正在进行中的全球新药三期临床试验结果的预测（@DemiurgeTech）。
因此，我们在这里基于AI提出的拓扑异构酶I型抑制剂和拓扑异构酶II型抑制剂的联合用药做为针对COVID-19危重症患者的新型候选治疗方案的科学假设，并公开邀请世界各地通过严谨设计的超说明书用药，验证伊立替康和依托泊苷的联合疗法是否能为COVID-19危重症患者带来临床受益。Demiurge敦促大众在任何相关临床数据公布之前，不应将任何拓扑异构酶I型抑制剂和拓扑异构酶II型抑制剂的联合用药做为等同于COVID-19的治疗药物擅自使用。
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